Absorption (food ↓)
- Food reduces drug bioavailability
- Binding, delayed dissolution or transport may contribute
- Some drugs therefore require fasting dosing
- Timing instructions are part of the prescription
- Do not assume all food effects are clinically trivial
Interaction at a glance
- Food reduces drug bioavailability
Mechanism
- Binding, delayed dissolution or transport may contribute
Timing / washout
- Some drugs therefore require fasting dosing
- Timing instructions are part of the prescription
Management
- Food reduces drug bioavailability
- Do not assume all food effects are clinically trivial
Self-check
- What mechanisms may reduce absorption with food?
Binding, delayed dissolution or transport. - What dosing condition do some food-reduced-absorption drugs require?
Fasting.
Drugs in this interaction (8)
All interaction examples · Open Absorption (food ↓) in the interactive console ↗