Absorption (food ↓)
- Food reduces drug bioavailability
- Binding, delayed dissolution or transport may contribute
- Some drugs therefore require fasting dosing
- Timing instructions are part of the prescription
- Do not assume all food effects are clinically trivial
Interaction at a glance
- Food reduces drug bioavailability
Mechanism
- Binding, delayed dissolution or transport may contribute
Timing / washout
- Some drugs therefore require fasting dosing
- Timing instructions are part of the prescription
Management
- Food reduces drug bioavailability
- Do not assume all food effects are clinically trivial
Self-check
- What does “Absorption (food ↓)” indicate?
Binding, delayed dissolution or transport may contribute.
Drugs in this interaction (8)
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