Triptans
- 5-HT1B/1D agonists for acute migraine
- Best when taken early in attack
- Sumatriptan has the most formulations
- Naratriptan/frovatriptan: slower, longer acting
- Vasoconstriction limits use in vascular disease
- Chest/neck pressure can occur without ischemia
- Not migraine-prevention drugs
Class at a glance
- 5-HT1B/1D agonists for acute migraine
Practical pearls
- Best when taken early in attack
Members / distinctions
- Sumatriptan has the most formulations
- Naratriptan/frovatriptan: slower, longer acting
Clinical role
- Vasoconstriction limits use in vascular disease
- Chest/neck pressure can occur without ischemia
- Not migraine-prevention drugs
Self-check
- Which triptan has the most formulations?
Sumatriptan.
Drugs in this class (7)
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