Thrombolytics (fibrinolytics)
- Convert plasminogen → plasmin
- Dissolve fibrin-rich thrombi
- Used in selected acute ischemic stroke/STEMI/PE
- Major bleeding, especially ICH, is key risk
- Timing and contraindication screening are critical
- Not the same as anticoagulation
Class at a glance
- Convert plasminogen → plasmin
Clinical role
- Dissolve fibrin-rich thrombi
- Used in selected acute ischemic stroke/STEMI/PE
Safety / monitoring
- Timing and contraindication screening are critical
- Not the same as anticoagulation
Safety distinctions
- Major bleeding, especially ICH, is key risk
Self-check
- What key adverse effect/risk occurs with Thrombolytics (fibrinolytics)?
Major bleeding, especially ICH, is key risk.
Drugs in this class (2)
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