Sublingual / buccal formulations
- Absorbed through oral mucosa
- Can bypass part of GI/first-pass exposure
- Onset may be faster than swallowed dosing
- Swallowing can change bioavailability
- Formulation instructions matter
Class at a glance
- Absorbed through oral mucosa
Practical pearls
- Can bypass part of GI/first-pass exposure
Other practical pearls
- Onset may be faster than swallowed dosing
Members / distinctions
- Swallowing can change bioavailability
- Formulation instructions matter
Self-check
- What can swallowing a sublingual/buccal product change?
Bioavailability.
- What exposure can oral-mucosal delivery partly bypass?
GI/first-pass exposure.
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