Selective estrogen receptor modulators (SERMs)
- Estrogen agonist/antagonist by tissue
- Tamoxifen: breast-cancer treatment/prevention
- Raloxifene: bone + breast-risk reduction
- Ospemifene: menopausal dyspareunia/GSM
- VTE risk is a major class concern
- Tamoxifen raises endometrial-cancer risk
- Bone effects differ by drug/menopause status
Class at a glance
- Estrogen agonist/antagonist by tissue
Safety / monitoring
- Raloxifene: bone + breast-risk reduction
- Ospemifene: menopausal dyspareunia/GSM
Clinical role
- Tamoxifen: breast-cancer treatment/prevention
- Bone effects differ by drug/menopause status
Safety distinctions
- VTE risk is a major class concern
- Tamoxifen raises endometrial-cancer risk
Self-check
- What are key clinical roles of tamoxifen?
Breast-cancer treatment and prevention.
Drugs in this class (4)
All drug classes · Open the interactive console ↗
