Pulmonary vasodilators
- Lower pulmonary vascular resistance
- Major pathways: NO, endothelin, prostacyclin
- Used mainly for pulmonary arterial hypertension
- Systemic hypotension + DDI risks vary
- Combination pathway therapy is common
- Not interchangeable across PH groups
Class at a glance
- Lower pulmonary vascular resistance
Clinical role
- Major pathways: NO, endothelin, prostacyclin
- Used mainly for pulmonary arterial hypertension
Practical pearls
- Combination pathway therapy is common
- Not interchangeable across PH groups
Safety / monitoring
- Systemic hypotension + DDI risks vary
Self-check
- Are pulmonary vasodilators interchangeable across PH groups?
No. - What are the major pulmonary-vasodilator pathways?
NO, endothelin and prostacyclin.
Drugs in this class (11)
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