Neuromuscular blockade reversal

Restore neuromuscular transmission after paralysis
Sugammadex encapsulates rocuronium/vecuronium
Neostigmine increases acetylcholine
Neostigmine requires antimuscarinic co-treatment
Depth of blockade determines success
Reversal does not replace ventilation monitoring

Class at a glance

Restore neuromuscular transmission after paralysis

Pharmacology

Depth of blockade determines success

Clinical role

Sugammadex encapsulates rocuronium/vecuronium
Neostigmine increases acetylcholine
Neostigmine requires antimuscarinic co-treatment

Safety / monitoring

Reversal does not replace ventilation monitoring

Drugs in this class (3)

Sugammadex ballicule — decagon mechanism diagram — Sugammadex

Neostigmine ballicule — decagon mechanism diagram — Neostigmine

Edrophonium ballicule — decagon mechanism diagram — Edrophonium

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