Immunomodulators (TNF inhibitors)
- Neutralize TNF signaling
- Major drugs across RA, IBD, psoriasis + SpA
- Screen for TB + hepatitis B before therapy
- Serious infection risk is the main concern
- Can worsen demyelination/heart failure in some
- Antidrug antibodies affect some agents
Class at a glance
Members / distinctions
- Major drugs across RA, IBD, psoriasis + SpA
- Screen for TB + hepatitis B before therapy
Practical pearls
- Can worsen demyelination/heart failure in some
- Antidrug antibodies affect some agents
Safety / monitoring
- Serious infection risk is the main concern
Drugs in this class (3)
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