Immunomodulators (S1P receptor modulators)
- Trap lymphocytes in lymphoid tissue
- S1P-receptor modulators used in MS/UC
- Lymphopenia + infection risk can occur
- First-dose bradycardia varies by agent
- Macular edema and liver effects are notable
- Abrupt withdrawal can permit disease rebound
Class at a glance
- Trap lymphocytes in lymphoid tissue
Practical pearls
- First-dose bradycardia varies by agent
Clinical role
- S1P-receptor modulators used in MS/UC
- Macular edema and liver effects are notable
Safety / monitoring
- Lymphopenia + infection risk can occur
- Abrupt withdrawal can permit disease rebound
Drugs in this class (4)
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