Immunomodulators (IL-23 pathway biologics)
- Biologics targeting IL-23 signaling
- Highly effective in psoriasis/PsA
- Some also treat inflammatory bowel disease
- Generally little routine lab toxicity
- Infection screening/vaccine planning still matter
- Dosing intervals can be long
Class at a glance
- Biologics targeting IL-23 signaling
Practical pearls
- Highly effective in psoriasis/PsA
Clinical role
- Some also treat inflammatory bowel disease
- Dosing intervals can be long
Safety / monitoring
- Generally little routine lab toxicity
- Infection screening/vaccine planning still matter
Self-check
- In which skin/joint diseases are IL-23 biologics highly effective?
Psoriasis/PsA. - Do infection screening and vaccine planning still matter with IL-23 biologics?
Yes.
Drugs in this class (3)
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