Chelators (iron)
- Bind excess iron for excretion
- Deferasirox: oral, once daily
- Deferiprone: oral; agranulocytosis monitoring
- Deferoxamine: parenteral; burdensome but effective
- Used for transfusional/chronic iron overload
- Renal/hepatic toxicity varies by agent
- Choice depends on iron burden + organ disease
Class at a glance
- Bind excess iron for excretion
Safety / monitoring
- Deferasirox: oral, once daily
- Deferiprone: oral; agranulocytosis monitoring
- Deferoxamine: parenteral; burdensome but effective
Clinical role
- Used for transfusional/chronic iron overload
- Choice depends on iron burden + organ disease
Safety distinctions
- Renal/hepatic toxicity varies by agent
Self-check
- What are Chelators (iron) used for?
Transfusional/chronic iron overload. - Which oral iron chelator requires agranulocytosis monitoring?
Deferiprone.
Drugs in this class (3)
All drug classes · Open Chelators (iron) in the interactive console ↗