Cephalosporins (first-generation)
- Beta-lactams with strong Gram-positive coverage
- Cephalexin oral; cefazolin IV are prototypes
- Useful for skin infections + surgical prophylaxis
- Limited enteric Gram-negative activity
- No meaningful atypical coverage
- Allergy and renal dosing still matter
Class at a glance
- Beta-lactams with strong Gram-positive coverage
Practical pearls
- Cephalexin oral; cefazolin IV are prototypes
Clinical role
- Useful for skin infections + surgical prophylaxis
- Limited enteric Gram-negative activity
- No meaningful atypical coverage
Other practical pearls
- Allergy and renal dosing still matter
Self-check
- When are Cephalosporins (first-generation) especially useful?
skin infections + surgical prophylaxis.
Drugs in this class (3)
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