Antivirals (influenza)

Work best when started early
Oseltamivir is the most broadly used
Zanamivir inhaled; avoid with airway disease
Baloxavir is single-dose cap-dependent inhibitor
Treat severe/hospitalized influenza regardless time
Resistance/host factors affect choice
Amantadine is obsolete from resistance

Class at a glance

Work best when started early

Pharmacology

Baloxavir is single-dose cap-dependent inhibitor

Clinical role

Oseltamivir is the most broadly used
Treat severe/hospitalized influenza regardless time
Resistance/host factors affect choice
Amantadine is obsolete from resistance

Safety / monitoring

Zanamivir inhaled; avoid with airway disease

Drugs in this class (2)

Oseltamivir ballicule — decagon mechanism diagram — Oseltamivir

Baloxavir marboxil ballicule — decagon mechanism diagram — Baloxavir marboxil

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