Antiseizure medications (ASMs, succinimides)

Ethosuximide class
Reduces thalamic T-type Ca2+ currents
Highly specific role: absence seizures
GI upset + fatigue are common
Rare serious blood/skin reactions occur
Not a broad-spectrum seizure drug

Class at a glance

Ethosuximide class

Practical pearls

Reduces thalamic T-type Ca2+ currents

Other practical pearls

GI upset + fatigue are common
Rare serious blood/skin reactions occur

Members / distinctions

Highly specific role: absence seizures
Not a broad-spectrum seizure drug

Drugs in this class (2)

Ethosuximide ballicule — decagon mechanism diagram — Ethosuximide

Methsuximide ballicule — decagon mechanism diagram — Methsuximide

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