Antidepressants (SNRIs)
- Antidepressants that add NET blockade
- MDD/anxiety; some also treat pain
- duloxetine: pain + GAD
- venlafaxine: strong anxiety evidence
- BP/HR can rise, especially at higher doses
- Sexual/GI effects resemble SSRIs
- Venlafaxine: prominent withdrawal
- Never combine with an MAOI
Class at a glance
- Antidepressants that add NET blockade
Members / distinctions
- Venlafaxine: prominent withdrawal
Clinical role
- MDD/anxiety; some also treat pain
- duloxetine: pain + GAD
- venlafaxine: strong anxiety evidence
- BP/HR can rise, especially at higher doses
Safety / monitoring
- Sexual/GI effects resemble SSRIs
- Never combine with an MAOI
Drugs in this class (5)
All drug classes · Open the interactive console ↗
