Anticoagulants (heparins & pentasaccharides)
- Parenteral anticoagulants via antithrombin
- UFH: rapid, titratable, fully reversible
- LMWH: predictable; less monitoring
- VTE, ACS, bridging + inpatient anticoagulation
- Bleeding + HIT are major risks
- Renal clearance matters more for LMWH
- Protamine reverses UFH better than LMWH
Class at a glance
- Parenteral anticoagulants via antithrombin
Safety / monitoring
- UFH: rapid, titratable, fully reversible
- LMWH: predictable; less monitoring
- Protamine reverses UFH better than LMWH
Practical pearls
- VTE, ACS, bridging + inpatient anticoagulation
Safety distinctions
- Bleeding + HIT are major risks
- Renal clearance matters more for LMWH
Drugs in this class (3)
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