Anti-CD20 antibodies
- Deplete CD20-positive B cells
- Rituximab/ofatumumab are key examples
- Uses span lymphoma, autoimmunity + MS
- Infusion/injection reactions are common
- HBV reactivation is a major screening issue
- Immunoglobulins/infection risk may accumulate
Class at a glance
- Deplete CD20-positive B cells
Practical pearls
- Rituximab/ofatumumab are key examples
Clinical role
- Uses span lymphoma, autoimmunity + MS
- Infusion/injection reactions are common
- HBV reactivation is a major screening issue
Safety / monitoring
- Immunoglobulins/infection risk may accumulate
Self-check
- Which viral reactivation is a major screening concern with anti-CD20 antibodies?
HBV. - Which cells do anti-CD20 antibodies deplete?
CD20-positive B cells.
Drugs in this class (2)
All drug classes · Open Anti-CD20 antibodies in the interactive console ↗